District Results of Presidential Elections 2000 for Afram Plains South
| Candidate | Votes | Percentage (%) |
| Mills | 10482 | 68.4 |
| Kuffuor | 3522 | 23 |
| Goosie | 350 | 2.3 |
| Hagan | 107 | 0.7 |
| Mahama | 275 | 1.8 |
| Wereko Brobby | 291 | 1.9 |
| Lartey | 291 | 1.9 |
| Valid | 0 | 0 |
| Rejected | 0 | 0 |
| Total Turnout | 0 | 0 |
| Registered | 0 |
