Avram Grant will leave as Ghana coach after supervising their third place playoff match against Burkina Faso on Saturday in Port Gentil.
Senior Ghana Football Association officials are reported to have told Reuters.
Grant signed an 18-month contract in December 2014 and was tasked to win the Africa Cup of Nations.
He was also supposed to put the Black Stars in a comfortable position in the 2018 FIFA World Cup qualifiers.
But the former Chelsea manager managed a runners-up spot at the last Nations Cup in Equatorial Guinea after losing on penalties to Ivory Coast.