All international flights to and from Chad are to be suspended for two weeks, starting from midnight on Thursday.
Cargo planes would still be allowed to enter the country, the government said in a statement.
Chad is also closing its land borders with Sudan and the Central African Republic after both reported cases of Coronavirus.
However, Chad's borders with Cameroon and Nigeria would remain open, despite the fact that they have also reported cases of the virus.
Gatherings of more than 50 people have also been banned in Chad.
To date, Chad has not recorded any cases of Coronavirus.