District Results of Presidential Elections 2000 for Sissala
| Candidate | Votes | Percentage (%) |
| Mills | 12262 | 42.8 |
| Kuffuor | 2512 | 8.8 |
| Goosie | 193 | 0.7 |
| Hagan | 193 | 0.7 |
| Mahama | 13024 | 45.5 |
| Wereko Brobby | 180 | 0.6 |
| Lartey | 287 | 1 |
| Valid | 0 | 0 |
| Rejected | 0 | 0 |
| Total Turnout | 0 | 0 |
| Registered | 0 |
