District Results of Presidential Elections 2000 for Affia-kwesimintin
| Candidate | Votes | Percentage (%) |
| Mills | 11612 | 22.6 |
| Kuffuor | 36764 | 71.5 |
| Goosie | 380 | 0.7 |
| Hagan | 1098 | 2.1 |
| Mahama | 1317 | 2.6 |
| Wereko Brobby | 61 | 0.1 |
| Lartey | 155 | 0.3 |
| Valid | 0 | 0 |
| Rejected | 0 | 0 |
| Total Turnout | 0 | 0 |
| Registered | 0 |
