After a busy weekend of FA Cup action, the Glo Premier League makes a return in midweek with some big clashes for the top two sides.
The league has 11 games to go and there are 33 points to vie for as the race for the top continues whiles the battle to escape relegation hots ups.
Asante Kotoko travel to the Golden City Park to take on champions Berekum Chelsea on Wednesday, knowing a win will take them further to winning the title.
The Porcupine Warriors hold a nine-point lead ahead of their rivals, Hearts of Oak, who also play a difficult game away to Medeama in Tarkwa.
For the Phobians who parted company with coach Nebojsa Vucicevic last Friday, they have a chance to respond against an inconsistent Medeama side.
But defeat could further heighten the tension within the capital side who have failed to live up to the ambition in recent seasons.
Aduana's push to maintain a top-four place will be tested at the Agyemang Badu Park as they welcome New Edubiase.
Wa All Stars will be seeking home comforts to turn around their campaign after having lost their last two games. The Blues play Ebusua Dwarfsat the Wa Park.
In-form AshantiGold could further improve on the log when they take on bottom side, Berekum Arsenal at the Len Clay Stadium.
At the Carl Reindorf Park, Liberty Professionals will host Wassaman United, who are attempting to play themselves out of the relegation zone. Mighty Jets are away to Tema Youth.
Bechem United play Heart of Lions at the Bechem Park to round up a packed fixture list for Wednesday's round of games.