Losing finalist in last season's MTN FA Cup, Asante Kotoko have been drawn against third-tier side Swallah Utd in this season's Round of 64.
Friday's live draw saw 16 premier league sides all enter the Cup competition after drawing a bye in the preliminary round.
Premiership side, Hearts of Oak were also paired with third-tier side as the Phobians would travel to Kintampo to face Sharp Arrows when the competition returns next year with matches scheduled for the weekend of 21, 22 and 23 January 2012.
The draw also produced two pairings in an all-premiership battle.
Berekum Chelsea would at home to Mighty Jets while Wassaman welcome Bechem United.
Great Olympics who defeated champions, FC Nania in the first round would be away to Golden Eyes.
Fixtures for Round of 64
Dunkwa Utd vrs Liberty Youth FC
King Faisal vrs Rainbow FC
Berekum Chelsea vs Mighty Jets
Sp Mirren vs Pokuase Utd
Deportivo vs Golden Boots
RTU vs Unity FC
Wassaman vsBechem United
Aduana Stars vs King Solomon
FY Juventus vs AshantiGold
Medeama vs Westlandes
Yagbon Stars vs Heart of Lions
Pure Joy vs Soccer Legends
Asante Kotoko vs Swallah Utd
K Dom FC/Unistar Academy vs Elmina Sharks
Eleven Wise vs Guan United/Dynamos Fc
Kintampo Sharp Arrows vs Hearts of Oak
Swedru All Blacks vs Liberty Professionals
Dormaa Kyenkyenkye vs Okwahu United
Yegola FC vs Universal Stars
Danbort FC vs Tamale Utrecht
Kfc Samosa vs Fcm Maamobi
Berekum Arsenal vs Kessben FC
Bazooka FC vs Tarkwa United
Samartex FC vs Amidaus Professionals
New Edubiase vs B. A. United
Inter Allies vs Berlin FC
Dwarfs vs Believers FC
Hasaacas vs Bolga All Stars
Upper East United vs Wa All Stars
Kotoku Royals vs B.A Stars/Bongo United
Tema Youth vs Portmouth FC
Golden Eyes vs Great Olympics