Daniel Opare and three other players have not made the trip to London for Ghana's international friendly against rivals, Nigeria on Tuesday.
The quartet including Ernest Sowah, Yaw Frimpong and Rashid Sumaila have headed home - Accra - from Nairobi, Kenya as Goran Stevanovic takes 19 players for the game at the Vicarage Road Stadium in Watford.
Opare, featured in the Black Stars' 2-0 away win against Sudan in Omdurman on Saturday to qualify for the 2012 African Nations Cup in Gabon and Equatorial Guinea while the rest were not in the team for the game.
Ghana squad
Goalkeepers: Adam Larsen Kwarasey (Stromgodest) Daniel Agyei (Liberty Professionals)
Defenders: Massawudu Alhassan (FC Genoa) John Paintsil (Leicester City), Isaac Vorsah (TSG Hoffenheim), John Mensah (Olympique Lyon), Lee Addy (Red Star Belgrade)
Midfielders: Samuel Inkoom (FC Dnipro), Kwadwo Asamoah, Emmanuel Agyeman-Badu (Udinese), Sulley Muntari (Inter Milan) Anthony Annan (Vitesse Arnhem), Albert Adomah (Bristol City), Abu Mohammed (Stromgodest), Derek Boateng (FC Dnipro) Quincy Owusu-Abeyie (Panathinaikos FC)
Strikers: Asamoah Gyan (Al Ain), Prince Tagoe (Bursaspor) Dominic Adiyiah (Karsiyaka).