25 burnt to death in Ghana
About 40 others were injured, many of them seriously, near Techiman town in the central farming region of Brong-Ahafo, some 400 kilometres (250 miles) northeast of the capital Accra.
Officials at a local hospital confirmed 25 people had died.
The victims who were burnt beyond recognition, had been scooping oil from the tanker that had just been involved in an accident, when the explosion occured.
It could not be immediately established what sparked the explosion. Incidents of people perishing in their dozens or even hundreds while looting fuel vehicles or pipelines are common in west Africa.
In Nigeria, Africa's second largest oil producer where nearly half of the 140 million people live in poverty, people rarely pass up on opportunities to gather free fuel from whatever source.
The fuel can always be sold in jerrycans to motorists at lower than pump price.
Ghana is in 2010 set to become the newest member of the elite club of Africa's oil producers following discoveries of reserves off its shores.
Police said they counted at least 21 bodies, and that more than 20 had been taken to hospital, some in a critical condition.
"On hearing the crash, the residents rushed to the scene and started siphoning the fuel off the tanker while others used bowls, buckets, enamelware -- anything they could lay hands on -- to scoop the fuel that was pouring out and unfortunately, there was a fire and an explosion and many of them got burnt," said Superintendent Solomon Nim.
Many West Africans have been killed attempting to salvage leaking fuel from crash sites. In August, at least 10 people died in Cameroon as they collected petrol from an overturned tanker which exploded. In September, a similar accident in Central African Republic killed 15.