Jonathan Mensah and Ebenezer Ofori are two Major League Soccer players named in Ghana's provisional 29-man squad for the 2019 Africa Cup of Nations.
Columbus Crew SC centre back Mensah and New York City FC midfielder Ofori.
The pair have 21 MLS starts between them this year.
If both players make the final cut, they could potentially be out for much of July should Ghana make a run to the final.
Mensah and Ofori are expected to join the Black Stars in Dubai, UAE for pre-season camping.
The 2019 Africa Cup of Nations starts on June 21 in Egypt.