The Black Queens were hammered 7-1 by Japan in an international friendly played in Nagasaki on Sunday, 1 April to miss out on winning the 2018 MS&AD Cup.
Ghana put up an impressive performance in the first half when striker Jane Ayiyiam cancelled out Nadeshiko's 14th minute goal.
But Iwabuchi ensured Japan regained their lead before the half hour mark.
In the second half, the Queens capitulated and conceded five more goals.
Last year, Ghana were hammered 8-0 by France in friendly played in Reims.
The friendly formed part of Ghana's preparations towards hosting this years African Women's Cup of Nations in Ghana.
The Queens recently won the WAFU Nations Cup and will use this exercise to improve ahead of the tournament in November.